| Regular Season | By Quarter Scores | |||||||||||
| Week | Date (Day) | Opponent | Location | Score | Result | Record | Overall | ||||
| 1 | Sep 7, 2025 (Sun) | @ Atlanta Falcons | Mercedes-Benz Stadium | 23 - 20 | Win | 1-0-0 | 1-0-0 | stats | standings | ||
| 2 | Sep 15, 2025 (Mon) | @ Houston Texans | NRG Stadium | 20 - 19 | Win | 2-0-0 | 2-0-0 | stats | standings | ||
| 3 | Sep 21, 2025 (Sun) | New York Jets | Raymond James Stadium | 29 - 27 | Win | 3-0-0 | 3-0-0 | stats | standings | ||
| 4 | Sep 28, 2025 (Sun) | Philadelphia Eagles | Raymond James Stadium | 25 - 31 | Loss | 3-1-0 | 3-1-0 | stats | standings | ||
| 5 | Oct 5, 2025 (Sun) | @ Seattle Seahawks | Lumen Field | 38 - 35 | Win | 4-1-0 | 4-1-0 | stats | standings | ||
| 6 | Oct 12, 2025 (Sun) | San Francisco 49ers | Raymond James Stadium | 30 - 19 | Win | 5-1-0 | 5-1-0 | stats | standings | ||
| 7 | Oct 20, 2025 (Mon) | @ Detroit Lions | Ford Field | 9 - 24 | Loss | 5-2-0 | 5-2-0 | stats | standings | ||
| 8 | Oct 26, 2025 (Sun) | @ New Orleans Saints | Caesars Superdome | 23 - 3 | Win | 6-2-0 | 6-2-0 | stats | standings | ||
| 10 | Nov 9, 2025 (Sun) | New England Patriots | Raymond James Stadium | 23 - 28 | Loss | 6-3-0 | 6-3-0 | stats | standings | ||
| 11 | Nov 16, 2025 (Sun) | @ Buffalo Bills | Highmark Stadium | 32 - 44 | Loss | 6-4-0 | 6-4-0 | stats | standings | ||
| 12 | Nov 23, 2025 (Sun) | @ Los Angeles Rams | SoFi Stadium | 8:20 PM EST | |||||||
| 13 | Nov 30, 2025 (Sun) | Arizona Cardinals | Raymond James Stadium | 1:00 PM EST | |||||||
| 14 | Dec 7, 2025 (Sun) | New Orleans Saints | Raymond James Stadium | 1:00 PM EST | |||||||
| 15 | Dec 11, 2025 (Thu) | Atlanta Falcons | Raymond James Stadium | 8:15 PM EST | |||||||
| 16 | Dec 21, 2025 (Sun) | @ Carolina Panthers | Bank of America Stadium | 1:00 PM EST | |||||||
| 17 | Dec 28, 2025 (Sun) | @ Miami Dolphins | Hard Rock Stadium | 1:00 PM EST | |||||||
| 18 | Jan 4, 2026 (Sun) | Carolina Panthers | Raymond James Stadium | 1:00 PM EST | |||||||
Tampa Bay Buccaneers Schedule - 2025