| Season | Date (Day) | Opponent | Location | Score | Result | W | L | T | |||||
| 1995 | Oct 29, 1995 (Sun) | Carolina Panthers | Foxboro Stadium | 17 - 20 | Loss | 0 | 1 | 0 | |||||
| 2001 | Jan 6, 2002 (Sun) | @ Carolina Panthers | Ericsson Stadium | 38 - 6 | Win | 1 | 1 | 0 | stats | ||||
| 2003 | Feb 1, 2004 (Sun) | Carolina Panthers | Playoff | Reliant Stadium | 32 - 29 | Win | 2 | 1 | 0 | stats | |||
| 2005 | Sep 18, 2005 (Sun) | @ Carolina Panthers | Bank of America Stadium | 17 - 27 | Loss | 2 | 2 | 0 | stats | ||||
| 2009 | Dec 13, 2009 (Sun) | Carolina Panthers | Gillette Stadium | 20 - 10 | Win | 3 | 2 | 0 | stats | ||||
| 2013 | Nov 18, 2013 (Mon) | @ Carolina Panthers | Bank of America Stadium | 20 - 24 | Loss | 3 | 3 | 0 | stats | ||||
| 2017 | Oct 1, 2017 (Sun) | Carolina Panthers | Gillette Stadium | 30 - 33 | Loss | 3 | 4 | 0 | stats | ||||
| 2021 | Nov 7, 2021 (Sun) | @ Carolina Panthers | Bank of America Stadium | 24 - 6 | Win | 4 | 4 | 0 | stats | ||||
| 2025 | Sep 28, 2025 (Sun) | Carolina Panthers | Gillette Stadium | 42 - 13 | Win | 5 | 4 | 0 | stats |
Patriots vs. Panthers History