| Regular Season | By Quarter Scores | |||||||||||
| Week | Date (Day) | Opponent | Location | Score | Result | Record | Overall | ||||
| 1 | Sep 7, 2025 (Sun) | Tennessee Titans | Empower Field at Mile High | 20 - 12 | Win | 1-0-0 | 1-0-0 | stats | standings | ||
| 2 | Sep 14, 2025 (Sun) | @ Indianapolis Colts | Lucas Oil Stadium | 28 - 29 | Loss | 1-1-0 | 1-1-0 | stats | standings | ||
| 3 | Sep 21, 2025 (Sun) | @ Los Angeles Chargers | SoFi Stadium | 20 - 23 | Loss | 1-2-0 | 1-2-0 | stats | standings | ||
| 4 | Sep 29, 2025 (Mon) | Cincinnati Bengals | Empower Field at Mile High | 8:15 PM EDT | |||||||
| 5 | Oct 5, 2025 (Sun) | @ Philadelphia Eagles | Lincoln Financial Field | 1:00 PM EDT | |||||||
| 6 | Oct 12, 2025 (Sun) | @ New York Jets | Tottenham Hotspur Stadium | 9:30 AM EDT | |||||||
| 7 | Oct 19, 2025 (Sun) | New York Giants | Empower Field at Mile High | 4:05 PM EDT | |||||||
| 8 | Oct 26, 2025 (Sun) | Dallas Cowboys | Empower Field at Mile High | 4:25 PM EDT | |||||||
| 9 | Nov 2, 2025 (Sun) | @ Houston Texans | NRG Stadium | 1:00 PM EST | |||||||
| 10 | Nov 6, 2025 (Thu) | Las Vegas Raiders | Empower Field at Mile High | 8:15 PM EST | |||||||
| 11 | Nov 16, 2025 (Sun) | Kansas City Chiefs | Empower Field at Mile High | 4:25 PM EST | |||||||
| 13 | Nov 30, 2025 (Sun) | @ Washington Commanders | Commanders Field | 8:20 PM EST | |||||||
| 14 | Dec 7, 2025 (Sun) | @ Las Vegas Raiders | Allegiant Stadium | 4:05 PM EST | |||||||
| 15 | Dec 14, 2025 (Sun) | Green Bay Packers | Empower Field at Mile High | 4:25 PM EST | |||||||
| 16 | Dec 21, 2025 (Sun) | Jacksonville Jaguars | Empower Field at Mile High | 4:05 PM EST | |||||||
| 17 | Dec 25, 2025 (Thu) | @ Kansas City Chiefs | GEHA Field at Arrowhead Stadium | 8:15 PM EST | |||||||
| 18 | Jan 4, 2026 (Sun) | Los Angeles Chargers | Empower Field at Mile High | 1:00 PM EST | |||||||
Denver Broncos Schedule - 2025