| Regular Season | By Quarter Scores | |||||||||||
| Week | Date (Day) | Opponent | Location | Score | Result | Record | Overall | ||||
| 1 | Sep 7, 2025 (Sun) | San Francisco 49ers | Lumen Field | 13 - 17 | Loss | 0-1-0 | 0-1-0 | stats | standings | ||
| 2 | Sep 14, 2025 (Sun) | @ Pittsburgh Steelers | Acrisure Stadium | 31 - 17 | Win | 1-1-0 | 1-1-0 | stats | standings | ||
| 3 | Sep 21, 2025 (Sun) | New Orleans Saints | Lumen Field | 44 - 13 | Win | 2-1-0 | 2-1-0 | stats | standings | ||
| 4 | Sep 25, 2025 (Thu) | @ Arizona Cardinals | State Farm Stadium | 23 - 20 | Win | 3-1-0 | 3-1-0 | stats | standings | ||
| 5 | Oct 5, 2025 (Sun) | Tampa Bay Buccaneers | Lumen Field | 4:05 PM EDT | |||||||
| 6 | Oct 12, 2025 (Sun) | @ Jacksonville Jaguars | TIAA Bank Field | 1:00 PM EDT | |||||||
| 7 | Oct 20, 2025 (Mon) | Houston Texans | Lumen Field | 10:00 PM EDT | |||||||
| 9 | Nov 2, 2025 (Sun) | @ Washington Commanders | Commanders Field | 8:20 PM EST | |||||||
| 10 | Nov 9, 2025 (Sun) | Arizona Cardinals | Lumen Field | 4:05 PM EST | |||||||
| 11 | Nov 16, 2025 (Sun) | @ Los Angeles Rams | SoFi Stadium | 4:05 PM EST | |||||||
| 12 | Nov 23, 2025 (Sun) | @ Tennessee Titans | Nissan Stadium | 1:00 PM EST | |||||||
| 13 | Nov 30, 2025 (Sun) | Minnesota Vikings | Lumen Field | 4:05 PM EST | |||||||
| 14 | Dec 7, 2025 (Sun) | @ Atlanta Falcons | Mercedes-Benz Stadium | 1:00 PM EST | |||||||
| 15 | Dec 14, 2025 (Sun) | Indianapolis Colts | Lumen Field | 4:25 PM EST | |||||||
| 16 | Dec 18, 2025 (Thu) | Los Angeles Rams | Lumen Field | 8:15 PM EST | |||||||
| 17 | Dec 29, 2025 (Mon) | @ Carolina Panthers | Bank of America Stadium | 1:00 PM EST | |||||||
| 18 | Jan 4, 2026 (Sun) | @ San Francisco 49ers | Levi's Stadium | 1:00 PM EST | |||||||
Seattle Seahawks Schedule - 2025